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(a,b) Representative images of xenograft tumors isolated from nude mice in the different groups. (c) Tumor volume at different time points. (d) Tumor weight at different time points. (e) Protein expression of NNMT, SIRT1, and GAP43. (f) Staining of tumor sections with H&E and Ki-67 (g) Percentage of positive cells in Ki-67 staining. Values are expressed as means ± SEM, * p < 0.05, ** p < 0.01, compared with DOX(−).
