Table 2.
Pellet size alteration and sphericity alteration during dissolution testing.
CHIT Pellets | ||||||
---|---|---|---|---|---|---|
Time (h) | d10 | d50 | d90 | Sphericity | Dmean | std |
0 | 0.75 | 0.83 | 0.93 | 0.97 | 0.84 | 0.093 |
2 | 0.69 | 0.75 | 0.83 | 0.98 | 0.76 | 0.081 |
4 | 0.69 | 0.76 | 0.84 | 0.98 | 0.78 | 0.082 |
6 | 0.69 | 0.77 | 0.88 | 0.95 | 0.78 | 0.1 |
HPMC Pellets | ||||||
d10 | d50 | d90 | Sphericity | Dmean | std | |
0 | 0.84 | 0.98 | 1.11 | 0.95 | 0.98 | 0.13 |
2 | 0.76 | 0.89 | 0.99 | 0.96 | 0.89 | 0.1 |
4 | 0.76 | 0.86 | 0.98 | 0.96 | 0.87 | 0.094 |
6 | 0.75 | 0.86 | 0.98 | 0.96 | 0.87 | 0.11 |
ALG Pellets | ||||||
d10 | d50 | d90 | Sphericity | Dmean | std | |
0 | 0.87 | 1 | 1.18 | 0.93 | 1.02 | 0.14 |
2 | 0.81 | 0.93 | 1.05 | 0.93 | 0.94 | 0.11 |
4 | 0.79 | 0.9 | 1.04 | 0.94 | 0.92 | 0.13 |
6 | 0.81 | 0.92 | 1.05 | 0.93 | 0.94 | 0.13 |