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. 2022 Jul 26;20:261. doi: 10.1186/s12916-022-02433-x

Table 2.

Distribution of phenotypes of cytochromes enzymes involved in the metabolism of citalopram, paroxetine, fluoxetine, and sertraline among the participants

Total Citalopram Fluoxetine Paroxetine Sertraline
N = 663 N = 202 N = 191 N = 107 N = 163
CYP2C19
 Poor/intermediate metabolizer, n 196 (30%) 58 (29%) 46 (28%)
 Normal metabolizer, n 268 (40%) 83 (41%) 66 (41%)
 Rapid/ultrarapid metabolizer, n 199 (30%) 61 (30%) 51 (31%)
CYP2D6
 Poor/intermediate metabolizer, n 462 (70%) 136 (71%) 70 (65%) 127 (78%)
 Normal metabolizer, n 191 (29%) 53 (28.9%) 34 (32%) 31 (19%)
 Rapid/ultrarapid metabolizer, n 10 (1%) 2 (0.1%) 3 (3%) 5 (3%)
CYP2C9
 Poor/intermediate metabolizer, n 234 (35%) 70 (37%)
 Normal metabolizer, n 429 (65%) 121 (63%)

Categorical data are presented as frequencies and percentages