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. 2022 Jun 26;10(7):1022. doi: 10.3390/vaccines10071022

Figure 1.

Figure 1

Pathogenesis of adult-onset Still’s disease (AOSD). AGEs = advanced glycation end products, DAMP = damage-associated molecular pattern, ER = endoplasmic reticulum, HLA = human leukocyte antigen, IFN = interferon, IL = interleukin, MAS = macrophage activation syndrome, MIF = macrophage inhibitory factor, NK cell = natural killer cell, NLRP3 = NOD-like receptor family pyrin domain-containing 3, PAMP = pathogen-associated molecular pattern, ROS = reactive oxygen species, Th1 = T helper 1, Th17 = T helper 17, TLR = Toll-like receptor, TNF = tumor necrosis factor, Treg = regulatory T cell.