Table 2.
Demographic and clinical data of patients included in the study between 2010–2011 (group 1) and 2018–2019 (group 2).
| Parameters | Group 1, 286 pts | Group 2, 433 pts | p |
|---|---|---|---|
| Age (years) | 72.8 ± 9.8 | 73.8 ± 10.4 | 0.1883 |
| Sex—male | 149 (52.1) | 193 (44.6) | 0.0479 |
| Myocardial infarction | 41 (14.5) | 57 (13.2) | 0.6097 |
| Congestive heart failure | 213 (74.5) | 317 (73.2) | 0.7822 |
| PAD | 22 (7.7) | 53 (12.2) | 0.0496 |
| ASC | 66 (23.2) | 156 (36) | 0.0002 |
| Dementia | 43 (15) | 23 (5.3) | <0.0001 |
| COPD (n, %) | 67 (23.4) | 71 (16.4) | 0.0191 |
| Uncomplicated DM | 52 (18.2) | 78 (18) | 0.9665 |
| Complicated DM | 22 (7.8) | 63 (14.5) | 0.0053 |
| Moderate-severe CKD | 81 (28.6) | 48 (11.1) | <0.0001 |
| Hemiplegia | 6 (2.1) | 7 (1.6) | 0.6309 |
| Leukemia | 3 (1) | 4 (0.9) | 1 |
| Lymphoma | 2 (0.7) | 2 (0.5) | 0.6498 |
| Neoplasm | 47 (16.5) | 48 (11.1) | 0.0364 |
| Metastasis | 11 (3.9) | 15 (3.5) | 0.7813 |
| Mild liver disease (n, %) | 102 (35.8) | 30 (6.9) | <0.0001 |
| Severe liver disease (n, %) | 11 (3.9) | 13 (3) | 0.5393 |
| AIDS (n, %) | 0 (0) | 0 (0) | 1 |
| HTN (n, %) | 216 (77.9) | 381 (88) | 0.0002 |
| Anemia (n, %) | 69 (30.1) | 140 (32.3) | 0.5621 |
| Creatinine (mg/dL) | 1.2 ± 0.5 | 1.2 ± 0.5 | 0.6362 |
| ClCr by MDRD equation (mL/min/1.73 m2) | 60.7 ± 20.3 | 61 ± 20.9 | 0.8743 |
| ACO at discharge (n, %) | 199 (69.6) | 377 (87.1) | <0.0001 |
| Use of antiplatelet drugs (n, %) | 72 (25.1) | 115 (26.5) | 0.67 |
| CHA2 DS2-VASc score | 3.9 ± 1.7 | 4.5 ± 1.6 | <0.0001 |
| HAS BLED score | 2.5 ± 1.1 | 2.2 ± 1.3 | 0.0001 |
| CCI | 6.2 ± 2.8 | 5.4 ± 2.1 | 0.0024 |
ACO = oral anticoagulation; AIDS = acquired immunodeficiency syndrome; ASC = cerebrovascular disease; CCI = Charlson comorbidity index; CKD = chronic kidney disease; ClCr = creatinine clearance; COPD = chronic obstructive pulmonary disease; DM = diabetes mellitus; HTN = arterial hypertension; MDRD equation = Modification of Diet in Renal Disease equations; MI = myocardial infarction; PAD = peripheral arterial disease. p-values marked with bold indicate statistically significant p-values.