Table 4.

Diagnostic performance of linearly blended M_0.6, standard virtual monoenergetic imaging (VMI) at 60 keV, and noise-optimized VMI+ series at 40 keV and 60 keV levels for the detection of portal vein thrombosis (PVT).

Parameter	M_0.6	60 keV VMI	40 keV VMI+	60 keV VMI+
Sensitivity	87% [0.77–0.94]	87% [0.77–0.94]	96% [0.89–0.99]	92% [0.84–0.97]
Specificity	92% [0.87–0.96]	97% [0.93–0.99]	96% [0.93–0.99]	97% [0.93–0.99]
AUC	0.94 [0.90–0.97]	0.95 [0.91–0.98]	0.99 [0.98–1.00]	0.97 [0.93–0.99]
p-value	p < 0.001	p = 0.001	N/A	p = 0.012

Sensitivity and specificity are presented as percentages with corresponding 95% confidence intervals (CI) in brackets. VMI = virtual monoenergetic imaging, VMI+ = noise-optimized virtual monoenergetic imaging, AUC = Area under the curve. p-values refer to the comparison with 40 keV VMI+ values.