Table 4.
Variables related to sepsis.
| Variables Related to Sepsis (Matched Cohort) | ||||
|---|---|---|---|---|
| Univariate Analysis | Multivariate Analysis | |||
| Variable | OR (ClL, CLU) | p Value | OR (ClL, CLU) | p Value |
| BMI (m2/kg) | 1.098 (1.026, 1.174) | 0.007 | ||
| Hemoadsorption | 0.308 (0.130, 0.730) | 0.008 | 0.42 (0.16, 1.07) | 0.07 |
| Euroscore II | 1.022 (1.003, 1.041) | 0.024 | ||
| Cardiogenic shock in last 48 h | 6.125 (2.616, 14.339) | <0.001 | ||
| Ventilated preop. | 3.326 (1.214, 9.110) | 0.019 | ||
| Staphylococcus spec. | 2.506 (1.126, 5.577) | 0.024 | 2.65 (1.04, 6.75) | 0.041 |
| CRP preop. | 1.104 (1.054, 1.158) | <0.001 | ||
| WBC preop. | 1.18 (1.046, 1.196) | 0.001 | ||
| Lactate preop. | 1.878 (1.114, 3.165) | 0.018 | ||
| Inotropes preop. | 7.266 (2.933, 18.002) | <0.001 | ||
| CPB duration | 1.006 (1.001, 1.011) | 0.011 | ||
| Aortic cros-clamp | 1.007 (1.000, 1.014) | 0.046 | ||
| Lactate end of surgery | 2.207 (1.519, 3.209) | <0.001 | ||
| Inotropes cumulative POD 1 | 1.047 (1.031, 1.065) | <0.001 | ||
| Inotropes cumulative POD2 | 1.05 (1.030, 1.071) | <0.001 | ||
| WBC POD1 | 1.222 (1.131, 1.320) | <0.001 | ||
| WBC POD2 | 1.258 (1.155, 1.370) | <0.001 | 1.28 (1.15, 1.43) | <0.001 |
| Lactate 24 h postop. | 2.644 (1.650, 4.236) | <0.001 | ||
| c-TnT POD1 | 1.351 (1.162, 1.572) | <0.001 | ||
| CK-MB POD 1 | 1.01 (1.004, 1.016) | <0.001 | ||
| CRP POD 1 | 1.088 (1.025, 1.156) | 0.006 | ||
| CRP POD2 | 1.056 (0.998, 1.116) | 0.059 | 1.07 (1.01, 1.14) | 0.021 |
| New RRT postop. | 7.142 (3.101, 16.452) | <0.001 | 4.93 (1.70, 14.26) | 0.003 |
| IABP postop. | 6.308 (1.485, 26.792) | 0.013 | ||
| FFPs transfused | 1.088 (1.020, 1.161) | 0.011 | ||
Multivariate analysis was performed for p < 0.05; BMI: body mass index; CK-MB: creatin kinase MB; CPB: cardiopulmonary bypass; CRP: C-reactive protein; c-TnT: c-troponin; Inotropes: (nor)-/ + epinephrine-/ + dobutamine; FFP: fresh frozen plasma; IABP: intra-aortic balloon pump; min: minute; preop: preoperative; postop: postoperative; POD: postoperative day; RRT: renal replacement therapy, WBC: white blood cells.