Table 6.
Univariate Analysis | Multivariate Analysis | |||
---|---|---|---|---|
Variable | OR (ClL, CLU) | p Value | OR (ClL, CLU) | p Value |
BMI | 1.068 (1.005, 1.135) | 0.034 | ||
Hemoadsorption therapy | 0.462 (0.225, 0.951) | 0.036 | 0.07 (0.01, 0.79) | 0.032 |
Staphylococcus spec. | 2.497 (1.223, 5.096) | 0.012 | ||
Endocarditis of 2 or more valves | 2.654 (1.025, 6.873) | 0.044 | ||
Cardiogenic chock in the last 48 h | 6.786 (3.047, 15.114) | <0.001 | ||
Inotropes preop. | 6.362 (2.932, 13.801) | <0.001 | 17.36 (1.77, 170.13) | 0.014 |
Preop Lactate | 2.147 (1.252, 3.679) | 0.005 | ||
Ventilated preop. | 5.576 (2.168, 14.338) | <0.001 | ||
WBC preop. | 1.129 (1.058, 1.204) | <0.001 | ||
CRP preop. | 1.082 (1.036, 1.130) | <0.001 | ||
CPB duration | 1.006 (1.002, 1.011) | 0.008 | ||
Aortic cross-clamp | 1.007 (1.001, 1.014) | 0.026 | ||
Lactate end of surgery | 2.637 (1.761, 3.948) | <0.001 | ||
Lactate 24 h postop. | 2.754 (1.712, 4.432) | <0.001 | 4.14 (1.01, 17.01) | 0.049 |
WBC POD1 | 1.173 (1.100,1.252) | <0.001 | ||
Inotropes cumulative POD1 | 1.053 (1.035, 1.071) | <0.001 | ||
Inotropes cumulative POD2 | 1.048 (1.028, 1.069) | <0.001 | 1.02 (1.00, 1.04) | 0.024 |
WBC POD2 | 1.202 (1.120, 1.289) | <0.001 | ||
c-TnT POD 1 | 1.365 (1.168, 1.595) | <0.001 | ||
CK-MB POD 1 | 1.009 (1.003, 1.015) | 0.003 | ||
eGFRCKD-EPI preop. | 0.984 (0.971, 0.998) | 0.022 | ||
New RRT postop. | 6.833 (3.174, 14.709) | <0.001 | 14.10 (1.57, 126.67) | 0.018 |
FFPs transfused | 1.151 (1.076, 1.230) | <0.001 | ||
RBCs transfused | 1.085 (1.025, 1.149) | 0.005 | 0.9 (0.78, 1.03) | 0.123 |
Drainage Output (ml) in 24 h | 1.001 (1.000, 1.001) | 0.004 | 1.004 (1.001, 1.006) | 0.002 |
IABP postop. | 4.278 (1.021, 17.922) | 0.047 |
Multivariate analysis was performed for p < 0.05; BMI: body mass index; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration—for the equation see Definitions; CK-MB: creatin kinase MB; CRP: C-reactive protein; c-TnT: c-troponin; Inotropes: (nor)-/ + epinephrine-/ + dobutamine; eGFR: estimated glomerular filtration rate; FFP: fresh frozen plasma; IABP: intra-aortic balloon pump; min: minute; preop: preoperative; postop: postoperative; POD: postoperative day; RBC: red blood cell concentrate; RRT: renal replacement therapy; WBC: White blood cells.