α-syn	alpha-synuclein
ACE	aldoxime chalcone ethers
ACh	acetylcholine
AChE	acetylcholinesterase
AMP	adenosine 5′-monophosphate
AMPK	AMP protein kinase
AR	adenosine receptors
ARE	antioxidant response elements
Aβ	beta-amyloid
A1R	adenosine A1 receptor
A1Rrat	adenosine A1 receptor rat whole brain membranes
A2AR	adenosine A2A receptor
A2ARrat	adenosine A2A receptor rat striatal membranes
BACE-1	β-site amyloid precursor cleaving enzyme 1
BBB	blood-brain barrier
BuChE	butyrylcholinesterase
eeBuChE	equine serum butyrylcholinesterase
CAT	catalase anti-oxidant markers
ChE	cholinesterase
ChEI	cholinesterase inhibitor
CNS	central nervous system
COMT	catechol-O-methyltransferase
COX-2	cyclooxygenase-2
CYP	cytochrome
DA	dopamine
D1R	dopamine D1 receptors
D2R	dopamine D2 receptors
ELISA	enzyme-linked immunosorbent assay
eeAChE	electric eel acetylcholinesterase
eNOS	endothelial NOS
GCase	glucocerebrosidase
GCL	glutamate cysteine ligase
GCLC	glutamate cysteine ligase catalytic subunit
GCLM	glutamate cysteine ligase modifier subunit
GTP	guanosine triphosphate
hMAO A	human monoamine oxidase A
hMAO B	human monoamine oxidase B
HO-1	heme oxygenase-1
H3R	histamine H3 receptor
iNOS	inducible nitric oxide synthases
IKK	ikappaB kinase
JNK	c-Jun N-terminal kinases
LB	Lewy bodies
LN	Lewy neurons
LPS	lipopolysaccharide
LRRK2	leucine-rich repeat kinase 2
MAO A	monoamine oxidase A
MAO B	monoamine oxidase B
MB-COMT	membrane-bound catechol-O-methyltransferase
MDA	malondialdehyde
MG	methylglyoxal
MM/GBSA	molecular mechanics with generalized Born and surface area solvation
MPTP	1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
rMAO A	rat brain mitochondria MAO A
rMAO B	rat brain mitochondria MAO B
ND	neurodegenerative disorders
NMDA	N-methyl-D-aspartate
NMS	non-motor symptoms
nNOS	neuronal nitric oxide synthases
NO	nitric oxide
NOS	nitric oxide synthases
Nrf2	nuclear factor erythroid 2-related factor 2
PAMPA assay	parallel artificial membrane permeability assay
PARP1	poly [ADP-ribose] polymerase 1
PD	Parkinson’s disease
PDE10A	phosphodiesterase 10A
PD-MCI	Parkinson’s disease–mild cognitive impairment
PD-D	Parkinson’s disease dementia
PET	positron emission tomography
p-LIMK1	phosphorylated LIM kinase 1
PSMA1	proteasome 20S subunit alpha 1
PSMB5	proteasome 20S subunit beta 5
PSMB7	proteasome 20S subunit beta 7
PSMB8	proteasome 20S subunit beta 8
ROCK2	pho-associated protein kinase 2
ROS	reactive oxygen species
SN	substantia nigra
SOD	superoxide dismutase
ThT	thioflavin T