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. 2022 Jul 21;29(7):5164–5178. doi: 10.3390/curroncol29070409

Table 1.

Baseline patient characteristics and factors with potential influence on baseline MoCA scores, in total and according to groups with distinct MoCA score trajectories.

Total
N = 298		 Very Poor Group
N = 19		 Poor Group
N = 24		 Fair Group
N = 113		 Good Group
N = 142		 p-Value
Age
 Mean (SD)
Gender, n (%)
 Male
 Female
Education, n (%) (1 missing)
 Compulsory
 Secondary
 College or university
Comorbidity, CCI
 Mean (SD)
Number of daily medications
 Mean (SD)
Geriatric depression scale ≥5, n (%)
 No
 Yes
73.6 (6.3)

157 (52.7)
141 (47.3)

90 (30.3)
120 (40.4)
87 (29.3)

1.1 (1.3)

5.4 (3.6)

236 (79.2)
62 (20.8)
77.7 (7.6)

12 (63.2)
7 (36.8)

6 (33.3)
11 (61.1)
1 (5.6)

1.5 (1.4)

8.7 (4.4)

12 (63.2)
7 (36.8)
76.3 (6.4)

9 (37.5)
15 (62.5)

17 (70.8)
5 (20.8)
2 (8.3)

1.4 (1.5)

7.2 (4.0)

17 (70.8)
7 (29.2)
74.7 (6.4)

73 (64.6)
40 (35.4)

42 (38.2)
44 (40.0)
24 (21.8)

1.3 (1.6)

5.7 (3.7)

88 (77.9)
25 (22.1)
71.8 (5.5)

63 (44.4)
79 (55.6)

25 (17.6)
58 (40.8)
59 (41.5)

0.8 (1.0)

4.5 (2.9)

119 (83.8)
23 (16.2)
<0.001 2

0.004 1


<0.001 1



0.003 2

<0.001 2

0.115 1
Number of physical impairments
 Mean (SD) (3 missing)
Fatigue
 Mean (SD) (3 missing)
RT treatment intent, n (%)
 Curative
 Palliative
Previous cancer treatment, n (%)
 Endocrine therapy
 Other systematic cancer therapy
 Cancer surgery/RT
Brain cancer/brain metastases, n (%)
 No
 Yes
1.3 (1.4)

37.4 (25.3)

162 (54.4)
136 (45.6)

57 (19.1)
90 (30.2)
182 (61.1)

282 (94.6)
16 (5.4)
3.2 (1.6) 3

45.1 (24.3)

3 (15.8)
16 (84.2)

1 (5.3)
8 (42.1)
10 (52.6)

16 (84.2)
3 (15.8)
1.9 (1.8)

38.9 (27.6)

13 (54.2)
11 (45.8)

7 (29.2)
5 (20.8)
16 (66.7)

22 (91.7)
2 (8.3)
1.5 (1.5) 4

38.2 (26.7)

47 (41.6)
66 (58.4)

27 (23.9)
33 (29.2)
60 (53.1)

108 (95.6)
5 (4.4)
0.8 (0.9)

35.5 (23.9)

99 (69.7)
43 (30.3)

22 (15.5)
44 (31.0)
96 (67.6)

136 (95.8)
6 (4.2)
<0.001 2

0.449 2

<0.001 1


0.079 1
0.499 1
0.091 1

0.169 1

Abbreviations: CCI, Charlson Comorbidity Index; ECOG PS, Eastern Cooperative Group performance status; Gy, Grey; p-value represents comparison of four groups, and p-values marked with bold indicate statistically significant differences. 1 χ2-test, 2 ANOVA, 3 One missing, 4 Two missing.