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. 2022 Jun 26;10(7):1294. doi: 10.3390/microorganisms10071294

Table 1.

Antiviral nucleoside analogs and the antiviral mechanisms/targets.

Antiviral Drugs Mechanisms/Targets Virus IC50/EC50 Value Reference
Remdesivir RdRp and nucleoside components SARS-CoV, MERS-CoV, MHV, PEDV, SARS-CoV-2 EC50 = 0.74 μmol/L [28,29,31]
Molnupiravir Genomic RNA of the virus SARS-CoV-2 - [33,34,35]