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Antiviral antimalarial drugs and the antiviral mechanisms/targets.
| Antiviral Drugs | Mechanisms/Targets | Virus | IC50/EC50 Value | Reference |
|---|---|---|---|---|
| Chloroquine | ACE2 receptor and proinflammatory cytokines | SARS-CoV-2 | - | [56] |
| Hydroxychloroquine | ||||
| NPQ | Affecting both entry and post-entry replication of the virus | HCoV-229E, HCoV-OC43, SARS-CoV-2 | IC50 = 2.05 ± 1.44, 5.83 ± 0.74, and 2.01 ± 0.38 μM, respectively | [61] |
