Table 4.

Antiviral natural antioxidants and the antiviral mechanisms/targets.

Antiviral Drugs	Mechanisms/Targets	Virus	IC50/EC50 Value	Reference
EGCG	Inhibiting viral attachment, entry, replication, and assembly	HIV, IAV, HBV, HCV, PRRSV, PCV2, PEDV	-	[69,70,71,72,73,74,75]
Betulinic acid, ursolic acid, aescin, lithocholic acid, nordihydroguaiaretic acid, caffeic acid phenethyl ester, and grape seed extract	Reducing virus-induced oxygen species production	PEDV	-	[76]
Cherry trees (phenolic compounds)	Inhibiting DPPH hydroxyl radical scavenging activity, reducing power capacity, and SOD-like activity	PEDV	-	[79]
Aloe vera (anthraquinones)	Antiviral genes, viral enzymes, and proteins	IAV, PPMV-1, HSV-1, PEDV	-	[82,83,84]