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8,14-DihydroxyEFV effect on sterol content in the brain. Data represent the mean ± SD of the measurements in individual 5XFAD mice (8 female and 8 male). * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001 as assessed by two-way ANOVA with Tukey’s multiple comparison test. The asterisk color indicates significance between female mice (pink), male mice (blue), or male-female animals (black). Cntr, control mice; Tx, treated mice.
