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8,14-DihydroxyEFV effect on the brain Aβ peptides. Data represent the mean ± SD of the measurements in individual 5XFAD mice (12 female and 12 male). *** p ≤ 0.001 as assessed by two-way ANOVA with Tukey’s multiple comparison test. The asterisk color indicates significance between female mice (pink) and male mice (blue). Cntr, control mice; Tx, treated mice.
