Table 1.
Baseline characteristics according to occult cancer status.
| Total N = 993 M(IQR)/N(%) |
Occult Cancer N = 53 M(IQR)/N(%) |
Absence of Cancer N = 940 M(IQR)/N(%) |
p | |
|---|---|---|---|---|
| Demographic data | ||||
| Age Age > 65 years |
67 (50–78) 519 (52.3) |
73 (66–82) 41 (77.4) |
66 (49–78) 478 (50.9) |
0.00119
0.0003 |
| Female | 528 (53.2) | 27 (50.9) | 501 (53.3) | 0.84 |
| BMI (N = 911) | 27 (24–31) | 27 (24.5–30) | 27 (23–31) | 0.66 |
| Cardiovascular risk factors | ||||
| Arterial hypertension | 486 (48.9) | 27 (50.9) | 459 (48.8) | 0.87 |
| History of smoking (active or former) (N = 965) Active |
403 (41.8) 158 (16.4) |
21 (40.4) 2 (3.8) |
382 (41.8) 156 (17.1) |
0.95 0.024 |
| Diabetes | 146 (14.7) | 6 (11.3) | 140 (14.9) | 0.60 |
| Dyslipidemia | 298 (30) | 16 (30.2) | 282 (30) | 1 |
| Obesity (N = 911) | 313 (33.3) | 15 (29.4) | 298 (33.5) | 0.65 |
| Héredity | 45 (4.5) | 1 (1.9) | 44 (4.7) | 0.50 |
| Comorbidities | ||||
| Ischemic heart disease | 44 (4.4) | 2 (3.8) | 42 (4.5) | 1 |
| Stroke/transient ischemic attack | 61 (6.1) | 4 (7.5) | 57 (6.1) | 0.56 |
| Lower-limb arteriopathy | 29 (2.9) | 2 (3.8) | 27 (2.9) | 0.66 |
| Chronic obstructive pulmonary disease | 52 (5.2) | 3 (5.7) | 49 (5.2) | 0.75 |
| Atrial fibrillation | 59 (5.9) | 3 (5.7) | 56 (5.9) | 1 |
| Chronic kidney disease | 513 (51.7) | 38 (71.7) | 475 (50.5) | 0.003 |
| 60 ≤ eGFR MDRD < 90 mL/min/1.73 m2 | 347 (34.9) | 27 (50.9) | 320 (34) | 0.018 |
| 30 ≤ eGFR MDRD < 60 mL/min/1.73 m2 | 138 (13.9) | 10 (18.9) | 128 (13.6) | 0.38 |
| 15 ≤ eGFR MDRD < 30 mL/min/1.73 m2 | 23 (2.3) | 1 (1.9) | 22 (2.3) | 1 |
| eGFR MDRD < 15 mL/min/1.73 m2 | 5 (0.5) | 0 | 5 (5.3) | 1 |
| Cognitive disorders | 105 (10.6) | 3 (5.7) | 102 (10.9) | 0.35 |
| Psychiatric disorders | 132 (13.3) | 5 (9.4) | 127 (13.5) | 0.53 |
| VTE risk factors | ||||
| Fracture/orthopedic surgery | 35 (3.5) | 1 (1.9) | 34 (3.6) | 1 |
| Surgery with anesthesia > 30 min | 78 (7.9) | 1 (1.9) | 78 (8.2) | 0.11 |
| VTE history | 319 (32.1) | 20 (37.7) | 299 (31.8) | 0.45 |
| Recent hospitalization for heart/respiratory failure < 3 months | ||||
| Myocardial infarction < 3 months | 12 (1.2) | 1 (1.9) | 11 (1.2) | 0.48 |
| Spinal cord injury | 7 (0.7) | 0 | 7 (7.4) | 1 |
| Thrombophilia | 1 (1) | 0 | 1 (1) | 1 |
| Paralysis | 49 (4.9) | 1 (1.9) | 48 (5.1) | 0.51 |
| Central catheter | 6 (0.6) | 0 | 6 (0.6) | 1 |
| Oral contraception/hormone replacement therapy/in vitro fertilization | 2 (0.2) | 0 | 2 (0.2) | 1 |
| Pregnancy | ||||
| Antithrombotic treatment at admission | ||||
| Antiplatelet | 179 (18) | 10 (18.9) | 169 (17.9) | 1 |
| Anticoagulant | 64 (6.4) | 7 (13.2) | 57 (6.1) | 0.07 |
BMI: body mass index; eGFR: estimated glomerular filtration rate; IQR: interquartile range; M: median; MDRD: modification of diet in renal disease; N: number; VTE: venous thromboembolism.