Table 2:

Results from the multinomial WQS for each of the 4 classes of compounds, as well as for all compounds in a discrete full mixture rsWQS models, comparing relative odds of ASD, DD, and OEC with TD, with positively constrained betas in estimating the weights, adjusted for covariates (sex, year of birth, homeowner status, child’s race, child’s age in months, and maternal metabolic conditions). In the discreet full mixture rsWQS models, weights were estimated by randomly selecting 6 chemicals across 1000 subsets. The table provides the distribution of OR estimates across 100 splits for each chemical class, and for the mixture of all chemical classes combined, in relation to each of the developmental outcomes, and for the mixture of all chemical classes combined.

		ASD vs TD				DD vs TD				OEC vs TD
Chemical Class Mixture		Mean	Median	5th PCT	95th PCT	Mean	Median	5th PCT	95th PCT	Mean	Median	5th PCT	95th PCT
				PCT	PCT			PCT	PCT			PCT	PCT
Phenols/Parabens	OR	1.50	1.46	1.04	2.10	2.40	2.25	1.05	4.59	1.65	1.58	0.94	2.50
Phthalates	OR	1.12	1.08	0.88	1.42	1.33	1.29	0.89	1.93	1.30	1.26	0.90	1.74
Pesticides	OR	1.10	1.11	1.02	1.19	1.05	1.05	0.93	1.19	1.11	1.11	0.99	1.25
Trace Elements	OR	1.17	1.16	0.88	1.46	1.75	1.68	1.19	2.51	1.22	1.18	0.80	1.77
Total Mixture	OR	1.84	1.86	1.08	2.70	3.44	3.09	1.43	7.04	2.20	2.07	1.07	3.93