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. 2022 Jul 14;58(7):932. doi: 10.3390/medicina58070932

Table 2.

Summary of study results.

Study Results References
The Nurses’ Health study
Peanut consumption and reduced risk of colorectal cancer in women: a prospective study in Taiwan.
Decreased risk of colorectal cancer (CRC) for those who consumed 2+ servings of nuts per weekSuggests protective effects of peanut consumption against CRC in women [20]
[21]
The European Prospective Investigation into Cancer and Nutrition (EPIC)Nut Consumption and Survival in Patients With Stage III Colon Cancer: Results From CALGB 89803 (Alliance) Even an intake of 16 g of nuts and seeds per day reduced incidence of CRC in women [22]
Both disease-free survival and overall survival in stage III CRC patients were significantly improved with tree nut consumption increase [23]
Walnut Phenolic Extract and Its Bioactive Compounds Suppress Colon Cancer Cell Growth by Regulating Colon Cancer Stemness
Suppression of cell growth in a dose-dependent manner
Inhibition of telomere maintenance
[24]
Walnut phenolic extracts reduce telomere length and telomerase activity in a colon cancer stem cell model
In cells treated with WPE, telomere length had significantly decreased in a dose-dependent manner
Telomerase activity was also observed to decrease proportionally with WPE concentration
[25]
The relationship between nut intake and risk of colorectal cancer: a case control study
Underlines the important role that nut consumption plays in the prevention of colon cancer, in both men and women, in all sub-sites of the colon [26]
Nut and peanut butter intake and the risk of colorectal cancer and its anatomical and molecular subtypes: the Netherlands Cohort Study
In women, in restricted cubic spline analyses, a significant inverse association was observed regarding the risk for rectal cancer and peanut, peanut butter and nut consumption
In the case of the male gender, only borderline significance was achieved upon examination of the inverse non-linear relation between nut or peanut consumption and rectal cancer risk
[27]