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. 2022 Jul 15;10(7):1130. doi: 10.3390/vaccines10071130

Figure 5.

Figure 5

T cell responses to SARS-CoV-2 mRNA vaccination. T cell response rates and magnitudes in LuTRs and HCs: Bars indicate proportion of patients with a T cell response against SARS-CoV-2 peptide pools at 2–4 weeks after second vaccination dose (A). Circles represent individual T cell responses; y axis indicates the number of spot-forming cells (SFCs) per 106 PBMCs. Dashed lines indicates mean SFCs per 106 PBMCs + 3 times the standard deviation for spike peptide pool reactivity calculated from pre-pandemic controls (B). Scatterplot of humoral and cellular immune responses in LuTRs. The x axis represents Elecsys® Anti-SARS-CoV-2 IgG titers (BAU/mL), with the vertical dashed line indicating the cutoff for seroconversion. The y axis represents SCFs per 106 PBMCs, with the horizontal dashed line indicating mean SFCs per 106 PBMCs + 3 times the standard deviation for spike peptide pool reactivity calculated from pre-pandemic controls (C).