Table 4.
Association between the genotypes for ACE I/D, ACE2 rs2285666, and AGTR2 rs1403543 and retinal vessel diameters.
| Polymorphism | Genotype | Veins Diameter | Arteries Diameter | ||
|---|---|---|---|---|---|
| Estimate (95% CI) | p | Estimate (95% CI) | p | ||
| ACE a | II | 1.96 (−9.18–13.09) | 0.73 | 1.75 (−7.57–11.08) | 0.71 |
| ID | −0.64 (−8.38–7.10) | 0.87 | 0.89 (−5.80–7.58) | 0.79 | |
| DD | Ref. | Ref. | |||
| Female b | |||||
| ACE2 | AA | −9.6 (−44.05–24.85) | 0.58 | −3.11 (−26.88–20.65) | 0.80 |
| GA | 14.21 (−14.29–42.71) | 0.32 | 10.94 (−10.52–32.41) | 0.31 | |
| GG | Ref. | Ref. | |||
| AGTR2 | AA | −2.43 (−26.30–21.44) | 0.84 | 13.16 (−4.54–30.86) | 0.14 |
| AG | 7.85 (−8.41–24.11) | 0.34 | 11.03 (−1.21–23.28) | 0.08 | |
| GG | Ref. | Ref. | |||
| Male b | |||||
| ACE2 | AA | 1.14 (−8.87–11.15) | 0.82 | −0.67 (−9.43–8.09) | 0.88 |
| GG | Ref. | Ref. | |||
| AGTR2 | AA | −3.55 (−11.99–4.88) | 0.41 | −6.41 (−13.69–0.87) | 0.08 |
| GG | Ref. | Ref. | |||
a Analysis adjusted to severity, sex, age, oxygen, LDH, and ferritin; b Analysis adjusted to severity, age, oxygen, LDH, and ferritin.