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Phenotypic switch of human coronary artery smooth muscle cells (HCASMCs). Atherosclerotic-mimic conditions (150 µM H2O2 and 40 ng/ mL TNF-α) trigger a phenotypic shift from the contractile to synthetic form: (A) representative photograph of HCASMCs under control conditions, exhibiting a classical contractile, elongated shape; (B) representative photograph of HCASMCs under atherosclerotic conditions, exhibiting a classical synthetic, rhomboid shape. Scale bar represents 50 µm.
