Table 3.

Experimental design and group treatment in rats.

Group Number	Treatment Groups	Dosage Regimen
Group I, Control	Sodium chloride 0.9% w/v (Saline)	A dose of 10 mL/kg bwt, at the same time as the test agents. Control for test groups, II, III, and IV.
Group II	GTN	GTN: 6 mg/kg bwt, 1 h before killing the rats.
Group III	l-NAME	l-NAME: 40 mg/kg bwt, at the same times as l-NAME treatment in group VII.
Group IV	TAA	TAA: 500 mg/kg bwt, at the same time as TAA treatment in the groups V, VI, and VII.
Group V, Experimental Dose 1	TAA + GTN (3 mg/kg bwt)	TAA: 500 mg/kg bwt + GTN: 3 mg/kg bwt, 1 h after TAA administration.
Group VI, Experimental Dose 2	TAA + GTN (6 mg/kg bwt)	TAA: 500 mg/kg bwt + GTN: 6 mg/kg bwt, 1 h after TAA administration.
Group VII, Experimental	TAA + l-NAME	TAA: 500 mg/kg bwt + l-NAME: 40 mg/kg bwt, 1 h after TAA administration.