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. 2022 Jul 12;14(7):1455. doi: 10.3390/pharmaceutics14071455

Figure 3.

Figure 3

Effect of incorporation of INI-4001 and INI-2002 on hydrodynamic diameter, polydispersity (PDI), and zeta potential in AddaS03-like emulsions. INI-4001 or/and INI-2002 were incorporated alone or in combination into AddaS03-like emulsions at “low” (L) 0.175 mM or “high” (H) 1.75 mM target concentrations. Dynamic light scattering was used to measure (A) hydrodynamic diameter (Z.Avg, nm), (B) PDI, and (C) zeta potential (mV) at a pH of 6.7–6.8. Physical properties are given as mean ± SEM with black dots representing each replicate emulsion (n = 4). A one-way ANOVA with a post hoc Tukey’s test for multiple comparisons demonstrated significant differences between group means within compound concentrations (**** p < 0.0001) or when compared or to the AddaS03-like vehicle (# p < 0.05, #### p < 0.0001).