Table 1.
A list of phytochemicals as anticancer agents for different cancer in clinical trial.
| Phytochemicals | Clinical Trial Type and Phase | Cancer/Conditions Type | References |
|---|---|---|---|
| Quercetin | For prevention, Phase not applicable | Prostate cancer | [84] |
| For prevention, Phase II | Squamous cell carcinoma | [84] | |
| Green tea catechins | For prevention, Phase II | High breast density and postmenopausal in women | [150] |
| For treatment, Phase II | Neoplasm and multiple myeloma | [150] | |
| For treatment, Phase II | Oral premalignant lesion | [153] | |
| For treatment, Phase II | Bladder cancer | [150] | |
| For prevention, Phase II | Tobacco use disorder | [150] | |
| For treatment, Phase I | lung carcinoma | [150] | |
| Green tea polyphenon E and Erlotinib | For prevention, Phase I | Lesions of head and neck cancer | [154] |
| Curcumin | For prevention, Phase II | Familial adenomatous polyposis | [155] |
| For treatment, Phase I | Advanced osteosarcoma | [150,156] | |
| For treatment, Phase II | Advanced pancreatic cancer | [157] | |
| For prevention, Phase I | Colon cancer | [150,158] | |
| Indole-3-carbinol/3,3-diindolylmethane (IC3/DIM) | For prevention, Phase II | Prostate cancer progression | [159] |
| For treatment, Phase II | Breast cancer | [150] | |
| For prevention, Phase I | Women carrying BRCA1 mutation | [160] | |
| (IC3/DIM) + Radical prostatectomy | For treatment, Phase I | Prostate cancer | [150,161] |
| Genistein | For prevention, Phase II | Patients with bladder cancer | [162] |
| Resveratrol | For prevention, Phase II | Colorectal cancer | [163] |
| Betulinic acid | For treatment, Phase I/II | Dysplastic nevi that can be change into melanoma | [164] |
| Ingenol mebutate | For prevention, phase I/II | Human non-melanoma skin cancer | [164] |