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Metformin plasmatic concentration boxplots (ng/mL), including medians, interquartile ranges, and outliers (filled circles). (A) rs1799853 (*1/*2) and rs1057910 (*1/*3) in CYP2C9. (B) rs1934969 (IVS8 109 A/T) in CYP2C9. Metformin to the left, metformin + glibenclamide to the right according to genotype. No statistical difference was found either intra-group or extra-group.
