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Metformin plasmatic concentration boxplots (ng/mL), including medians, interquartile ranges, and outliers (filled circles). From left to right: C/T of rs1128503; G/G of rs2032582; C/C of rs1045642; T/T of rs1045642, treated with metformin. The following boxplots correspond to the same genotypes under combined therapy. Only C/T of rs1128503 reported significant differences in both groups (* p = 0.002).
