Table 7.
Multiple logistic regression on HbA1c no-control using a dominant genotype model for SLC22A1 and ABCB1 (n = 103).
| OCT 1 | |||||
| Variable | B | Standard Error | p- Value | OR (IC95%) | |
| Age (years) | −0.066 | 0.030 | 0.026 * | 0.936 (0.883–0.992) | |
| BMI ≥ 25 Kg/m2 | 1.953 | 0.967 | 0.043 * | 7.049 (1.059–46.895) | |
| rs72552763 GAT |
rs622342 A |
−0.642 | 0.593 | 0.279 | 0.526 (0.165–1.683) |
| Treatment (metformin + glibenclamide) |
2.893 | 0.653 | <0.001 * | 18.05 (5.015–64.969) | |
| Treatment period (years) | 0.232 | 0.072 | 0.001 * | 1.261 (1.094–1.452) | |
| ABCB1 | |||||
| Age (years) | −0.072 | 0.030 | 0.017 * | 0.930 (0.877–0.987) | |
| BMI ≥ 25 Kg/m2 | 2.211 | 1.088 | 0.042 * | 9.128 (1.083–76.966) | |
| rs1128503 C |
rs2032582 G |
−1.026 | 0.738 | 0.164 | 0.358 (0.084–1.522) |
| Treatment (metformin + glibenclamide) |
2.887 | 0.666 | <0.001 * | 17.933 (4.858–66.205) | |
| Treatment period (years) |
0.240 | 0.072 | 0.001 * | 1.271 (1.105–1.462) | |
B: Regression coefficient; OR: odds ratio; IC95%: 95% confidence interval. * Statistical significance (p < 0.05).