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. 2022 Jul 17;14(14):2929. doi: 10.3390/nu14142929

Figure 2.

Figure 2

Effect of SBH on the changes in body weights in HFHCD-induced obese mice. Male mice were fed normal chow (Nor, n = 8) or HFHCD for 6 weeks, and then were administered HFHCD with Sim as a positive control (Sim, 5 mg/kg/d, n = 7), SBH (100 mg/kg/d, n = 7), or a vehicle (HFHC only, n = 7), as depicted in the experimental schedule (A). Body weights of the experimental mice were measured every week during the entire experimental period (B). Significant differences between the groups were assessed using two-way ANOVA with Tukey’s multiple comparison test. ## p < 0.01, ### p < 0.001 compared with Nor; *** p < 0.001 compared with HFHC. Nor, normal control group; HFHC, high-fat and high-cholesterol diet group; Sim, HFHC diet plus Sim group; SBH, HFHC diet plus SBH group.