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. 2022 Jul 14;10(7):1122. doi: 10.3390/vaccines10071122

Table 3.

Risk factors for the seroconversion of neutralizing antibody among BNT162b2 recipients.

Adjusted OR * 95% CI
BNT162b2 (one dose)
Day 21
Antibiotic usage 0.26 0.08–0.96
Age ≥ 60 years 0.34 0.13–0.95
Male sex 0.14 0.05–0.34
DM 0.42 0.12–1.66
Overweight/obesity 0.92 0.37–2.29
Hypertension 1.07 0.44–2.82
Raised LDL (≥3.4 mmol/L) 3.82 1.01–25.4
Smoking 1.14 0.22–9.40
Alcohol use 1.02 0.26–5.20
Moderate/severe hepatic steatosis (CAP ≥ 268 dB/M) 2.48 0.80–8.83
BNT162b2 (two doses)
Day 56
Antibiotic usage 0.03 0.001–1.15
Age ≥ 60 years 0.38 0.006–69.18
Male sex NA * NA *
DM 0.02 0.0002–2.78
Overweight/obesity 0.58 0.008–27.85
Hypertension 0.40 0.008–25.06
Raised LDL (≥3.4 mmol/L) 0.56 0.01–101.48
Smoking NA * NA *
Alcohol use NA * NA *
Moderate/severe hepatic steatosis (CAP ≥ 268 dB/M) NA * NA *

* adjusted OR and 95% CI could not be derived due to the absence of negative serological response among all female patients, smokers, those who used alcohol and those with moderate/severe hepatic steatosis. Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval; DM, diabetes mellitus; LDL, low density lipoprotein; CAP, controlled attenuated parameter.