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Schematic of the microneedle device for hair regrowth. (A) Our DMN (PVP-based microneedle loaded with RAPA-PLGA and EGCG-KE NPs) penetrate the skin. (B) The microneedles dissolve rapidly and release nanoparticles and drug transport into the hair follicle niche. (C) Drugs can activate the healthy hair cycle, accelerate the transition of hair follicles from telogen to anagen, and promote hair regrowth.
