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. 2022 Jun 30;14(7):1447. doi: 10.3390/v14071447

Table 2.

This table shows that the 2 times exposure format in the healed groups lead to significantly higher neutralizing antibody titres than the disease alone. An asymptomatic re-exposure to the virus triggers a high antibody level in the blood. Interestingly, the intranasal PBS before IN virus exposure resulted in less antibody production possibly as result of severe disease. Students t-test p: level of significance, ns: not significant.

Group/Way of Infection IN = Intranasal IOC = Epiocular G4 G2 G3 G1
G4 Preventive /IOC infection X ns p 0.0013 p 0.0013
G2 Preventive /IN infection X p 0.0051 p 0.0025
G3 preventive PBS /IOC X ns
G1 Preventive PBS /IN X