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. Author manuscript; available in PMC: 2022 Jul 26.
Published in final edited form as: J Leukoc Biol. 2020 Feb 28;108(1):139–149. doi: 10.1002/JLB.3AB0220-311R

FIGURE 5. Charcot-Leyden crystal protein (CLC-P)/Gal-10 microdomains with high density are distributed at the eosinophil plasma membrane.

FIGURE 5

(A) Arrowheads indicate plasma membrane regions (microdomains) of resting eosinophils in which CLC-P/Gal-10 is concentrated. (B and Bi) The membrane area occupied by these microdomains (highlighted in green in Bi) was measured. (C) Quantitative imaging analyses revealed that 60% of the plasma membrane contains high-density-CLC-P/Gal-10 microdomains with a mean of one microdomain localized in each linear micrometer of this membrane. Note in (A) that some scattered labeling on the nucleus (N). Data are representative of 3 patients. A total of 37 cells showing the entire cell profile and nucleus was analyzed using Fiji software