Table A1.
Raw value group averages of each spontaneous inhibitory postsynaptic current (sIPSC) parameter tested.
| Alcohol Exposure | Sex | sIPSC Property | Baseline | 100 nM CRF | Baseline | 200 nM CRF | Baseline | 400 nM CRF | Baseline | R121919 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | |||
| Naïve | Male | Frequency (Hz) | 2.99 | 0.68 | 3.93 | 0.99 | 1.13 | 0.23 | 1.85 | 0.38 | 3.14 | 0.90 | 3.63 | 1.02 | 3.16 | 0.77 | 2.86 | 0.68 |
| Amplitude (pA) | 62.98 | 7.63 | 61.77 | 6.76 | 70.07 | 10.07 | 66.88 | 6.86 | 59.91 | 6.25 | 56.49 | 5.68 | 79.49 | 9.00 | 81.41 | 10.59 | ||
| Rise Time (ms) | 2.57 | 0.13 | 2.59 | 0.11 | 2.61 | 0.14 | 2.54 | 0.10 | 2.55 | 0.08 | 2.61 | 0.12 | 2.33 | 0.08 | 2.49 | 0.11 | ||
| Decay Time (ms) | 9.46 | 1.16 | 9.68 | 0.84 | 9.68 | 0.84 | 8.23 | 1.04 | 9.41 | 0.85 | 9.61 | 0.80 | 10.28 | 1.27 | 11.32 | 1.43 | ||
| n | 9 | 12 | 11 | 9 | ||||||||||||||
| Female | Frequency (Hz) | 1.48 | 0.36 | 1.52 | 0.28 | 1.73 | 0.58 | 1.61 | 0.49 | 1.52 | 0.34 | 1.94 | 0.58 | 2.25 | 0.58 | 2.01 | 0.51 | |
| Amplitude (pA) | 66.42 | 5.97 | 64.47 | 6.52 | 65.71 | 5.13 | 66.58 | 4.94 | 57.95 | 5.77 | 69.99 | 9.01 | 68.21 | 6.96 | 65.28 | 6.99 | ||
| Rise Time (ms) | 2.73 | 0.11 | 2.60 | 0.11 | 2.04 | 0.11 | 2.19 | 0.15 | 2.65 | 0.12 | 2.65 | 0.10 | 2.84 | 0.16 | 3.01 | 0.19 | ||
| Decay Time (ms) | 7.47 | 0.82 | 7.77 | 0.87 | 5.92 | 0.81 | 6.57 | 1.03 | 7.76 | 1.27 | 8.74 | 1.19 | 9.95 | 0.98 | 11.30 | 1.07 | ||
| n | 10 | 9 | 8 | 10 | ||||||||||||||
| Dependent | Male | Frequency (Hz) | 3.30 | 0.40 | 3.56 | 0.47 | 1.43 | 0.29 | 2.25 | 0.68 | 2.63 | 0.54 | 3.14 | 0.68 | 1.79 | 0.42 | 1.48 | 0.37 |
| Amplitude (pA) | 85.01 | 10.06 | 83.44 | 13.25 | 61.75 | 7.82 | 62.05 | 7.78 | 80.04 | 10.23 | 78.06 | 12.82 | 57.55 | 6.56 | 59.45 | 6.47 | ||
| Rise Time (ms) | 2.42 | 0.06 | 2.48 | 0.06 | 2.63 | 0.09 | 2.61 | 0.10 | 2.56 | 0.07 | 2.56 | 0.06 | 3.14 | 0.16 | 3.09 | 0.18 | ||
| Decay Time (ms) | 10.20 | 1.03 | 10.16 | 0.92 | 9.71 | 1.44 | 8.87 | 1.28 | 10.61 | 0.72 | 9.91 | 0.87 | 12.68 | 1.20 | 13.04 | 1.02 | ||
| n | 9 | 9 | 11 | 10 | ||||||||||||||
| Female | Frequency (Hz) | 2.42 | 0.56 | 2.42 | 0.56 | 1.50 | 0.21 | 2.57 | 0.57 | 1.63 | 0.23 | 2.13 | 0.37 | 1.93 | 0.62 | 1.68 | 0.48 | |
| Amplitude (pA) | 59.18 | 3.40 | 53.49 | 2.23 | 95.01 | 15.07 | 112.62 | 21.57 | 62.84 | 8.16 | 68.50 | 15.50 | 71.30 | 12.03 | 62.58 | 9.93 | ||
| Rise Time (ms) | 2.82 | 0.25 | 2.73 | 0.27 | 2.23 | 0.09 | 2.29 | 0.07 | 2.61 | 0.19 | 2.72 | 0.20 | 3.10 | 0.18 | 3.19 | 0.16 | ||
| Decay Time (ms) | 12.09 | 1.15 | 10.84 | 1.17 | 8.45 | 0.88 | 9.15 | 1.11 | 10.81 | 0.86 | 10.14 | 0.95 | 11.47 | 1.28 | 11.70 | 1.14 | ||
| n | 8 | 11 | 9 | 9 | ||||||||||||||