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. 2022 Jul 17;15(7):881. doi: 10.3390/ph15070881

Figure 8.

Figure 8

(A) Apoptosis of MDA-MB-231 cells treated for 12 h with saline (control), 5-FU, PTX, 5-FU+PTX, 5-FU+PTX Lps, or KLA-5-FU+PTX Lps, as determined by flow cytometry. (B) Effect of different formulations on the mitochondrial membrane potential of MDA-MB-231 cells. * p < 0.05, *** p < 0.001. 5-FU, 5-fluorouracil; PTX, paclitaxel; 5-FU/PTX, mechanically mixed free 5-FU and free PTX; 5-FU/PTX Lps, unmodified liposomes co-loaded with 5-FU and PTX; KLA-5-FU/PTX Lps, KLA-modified liposomes co-loaded with 5-FU and PTX. PI-A, propidium iodide channel; FITC-A, FITC channel.