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(A) Body weight of tumor-free mice treated with different formulations. (B) Histopathological examination of the heart, liver, spleen, lung, and kidney of tumor-free mice treated with different formulations. Original magnification, 400×. 5-FU, 5-fluorouracil; PTX, paclitaxel; 5-FU/PTX, mechanically mixed free 5-FU and free PTX; 5-FU/PTX Lps, unmodified liposomes co-loaded with 5-FU and PTX; KLA-5-FU/PTX Lps, KLA-modified liposomes co-loaded with 5-FU and PTX.
