Table 1.
Physical properties of blank, 5-FU/PTX, and KLA-5-FU/PTX Lps.
| Liposomes | Size/nm | PDI | Zeta Potential/mV |
EE%/DL% (5-FU) |
EE%/DL% (PTX) |
|---|---|---|---|---|---|
| Blank Lps | 123.68 ± 4.63 | 0.243 ± 0.015 | −17.87 ± 2.56 | - | - |
| 5-FU/PTX Lps | 125.27 ± 2.08 | 0.154 ± 0.009 | −16.51 ± 3.62 | 84.75 ± 1.24/ 8.61 ± 1.68 |
82.36 ± 3.82/ 6.92 ± 1.54 |
| KLA-5-FU/PTX Lps | 130.56 ± 3.14 | 0.238 ± 0.011 | 16.83 ± 1.95 | 82.81 ± 2.16/ 7.99 ± 1.36 |
80.47 ± 2.39/ 6.53 ± 1.03 |
All preparations were tested in triplicate. 5-FU, 5-fluorouracil; PTX, paclitaxel; Lps, liposomes; PDI, polydispersity index; EE, entrapment efficiency; DL, drug loading efficiency.