Table 1.

Multivariate Statistical Analysis variables.

Symbol	Short Description
Network Topology
DBA	Degree-based assortativity
Dy	Diadicity
H	Heterophilicity
HBAKD	Hydrophobicity-based assortativity
abtw	Average node betweenness centrality
acc	Average node clustering coefficient
adeg	Average node degree
asp	Average shortest path
aclose	Average node closeness centrality
E	Graph energy
Molecular Structure
$R_G$	Radius of gyration
$R_{Gh}$	The radius of gyration of hydrophobic residues
$R_{Gp}$	The radius of gyration of polar residues
corrHBKD	Hydrophobic core probability
$\rho$	Mass density
MFD	Mass fractal dimension
$\epsilon$	Porosity (void fraction)
AS	Asymmetry index