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. 2022 Jun 24;14(7):1332. doi: 10.3390/pharmaceutics14071332

Figure 2.

Figure 2

Antibiofilm peptides derived from the natural P. poeyana lead molecule Pom-1. (A) Illustration of the original AMP Pom-1 and its six derivatives (Pom-1A to Pom-1F) as ribbon models with QUARK and SwissModel, their amino acid sequences, and schematic representation of the α-helical structures. (B) Properties of Pom-1 and its derivatives calculated with ExPASy ProtParam [66]. Given are the theoretical isoelectric point (pI), the aliphatic index, and the grand average hydropathy index (GRAVY). These properties influence the mode and level of antimicrobial activity [31].