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. 2022 Jun 29;10(7):1315. doi: 10.3390/microorganisms10071315

Table 1.

Differences in risk factors, age of first presentation, and recurrence rates for CDI between IBD and general population. PPIs—proton-pump inhibitors, OR—odds ratio, HR—hazard ratio.

IBD Population General Population
Impact of PPIs use on risk of CDI 0.98 OR [0.54, 1.78] [15] 1.99 OR [1.73, 2.30] [16]
Impact of Antibiotics use on risk of CDI 1.85 OR [1.36, 2.52] [15] 3.55 OR (2.56–4.94) [17]
Impact of Steroids use on risk of CDI 0.96 [0.55, 1.69] [15] 1.81 OR (1.15–2.84) [18]
Difference in hospital mortality in patients with CDI 3.64 OR [2.66, 4.98] [15] 1.899 OR [1.269–2.840] [19]
Difference in average age of first CDI presentation 47.5 year for UC, 41 year for CD [14] 55 year [13]
Difference in recurrence rates of CDI 13% [12] 7% [12]
HR for rCDI between IBD and not IBD population HR: 2.28; 95% CI: 1.16–4.48, p < 0.001 [12]