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. 2022 Jul 3;10(7):1346. doi: 10.3390/microorganisms10071346

Table 5.

SCFA production in pH-controlled miniature fecal batch cultures supplemented with cranberry pomace or cranberry preparative HPLC fraction 2 (extract 2) at 0, 24 and 48 h.

Negative Control Inulin Cranberry Pomace Cranberry Extract 2
SCFA Time
Acetate t0 10.55 (3.29) 12.62 (3.15) 7.67 (1.57) 4.49 (0.82)
t24 8.98 (1.38) 21.93 (2.12) a 19.57 (2.64) ± 18.15 (1.78) ±
t48 14.23 (0.87) 20.11 (2.14) a 20.73 (2.58) ± 17.12 (1.27) ±
Propionate t0 3.37 (3.29) 2.92 (3.15) 1.62 (1.57) 0.76 (0.82)
t24 2.31 (1.38) 5.76 (2.12) 7.53 (2.64) b 7.73 (1.78) *a
t48 4.27 (0.87) 6.43 (2.14) 8.41 (2.58) ± 9.40 (1.27) *a
Butyrate t0 3.90 (2.54) 3.39 (2.17) 2.34 (1.02) 0.36 (0.62)
t24 4.54 (3.96) 26.23 (15.58) ± 18.39 (3.55) *a 17.01 (6.51) *a
t48 6.52 (4.69) 25.97 (12.47) ± 22.57 (3.02) ** 15.31 (9.29) ±
Valerate t0 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
t24 2.62 (3.43) 0.00 (0.00) 2.70 (2.53) 0.00 (0.00)
t48 2.88 (2.96) 0.47 (0.81) 4.52 (0.91) * 0.00 (0.00)
Isobutyrate t0 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
t24 2.26 (1.32) ± 0.00 (0.00) a 1.26 (2.18) 1.21 (2.10)
t48 2.12 (1.68) 0.95 (1.64) 1.72 (2.98) 1.79 (2.46)
Isovalerate t0 0.00 (0.00) 0.00 (0.00) 0.00 (0.00) 0.00 (0.00)
t24 2.74 (0.85) * 0.00 (0.00) a 1.09 (1.89) 1.17 (1.30)
t48 2.25 (1.04) 0.00 (0.00) 2.47 (1.58) * 0.85 (1.48)

Short chain fatty acid concentrations (mM) during fermentations. Standard deviation is shown in parentheses (n = 3). Significant differences to control at same time point denoted by a (p < 0.05), b p < 0.01). * Significant differences from value of same substrate at 0 h, p ≤ 0.05; ** significant differences from value 0 h p < 0.01; ± non-significant trend, p ≤ 0.1.