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. 2022 Jun 22;29(7):4438–4454. doi: 10.3390/curroncol29070353

Table 1.

Sample characteristics.

Time-Dependent Variables N Total Sample Mean SD
BIS T0 218 4.46 5.75
BIS T1 148 7.54 7.34
BIS T2 141 5.83 6.22
BIS T3 117 5.57 6.84
HADS ANXIETY T0 219 6.02 4.65
HADS ANXIETY T1 146 4.67 3.97
HADS ANXIETY T2 140 4.11 3.71
HADS ANXIETY T3 119 3.60 3.43
HADS DEPRESSION T0 219 3.72 3.99
HADS DEPRESSION T1 146 4.15 3.80
HADS DEPRESSION T2 141 3.46 4.42
HADS DEPRESSION T3 119 2.54 3.23
FACT PHYSICAL T0 222 23.15 5.52
FACT PHYSICAL T1 151 19.80 6.40
FACT PHYSICAL T2 144 23.17 4.67
FACT PHYSICAL T3 123 23.71 5.08
FACT HEAD NECK T0 217 35.89 7.80
FACT HEAD NECK T1 149 29.15 7.64
FACT HEAD NECK T2 143 33.88 7.03
FACT HEAD NECK T3 118 35.64 7.94
DISFIGUREMENT T0 222 1.40 1.18
DISFIGUREMENT T1 181 2.04 1.70
DISFIGUREMENT T2 126 1.85 1.28
DISFIGUREMENT T3 103 1.82 1.32
N Total Sample Frequency Percent
Treatment—3 months 215
  -Surgery alone 37 17
  -Radiotherapy alone 21 10
  -Chemotherapy alone 5 2
  -Surgery and radiotherapy 23 11
  -Radiation and chemotherapy 99 46
  -Surgery and radiotherapy and chemotherapy 30 14
Treatment—6 months 6
  -Surgery alone 3 50
  -Radiotherapy alone 1 17
  -Chemotherapy alone 1 17
  -Surgery and radiotherapy 0 0
  -Radiation and chemotherapy 1 17
  -Surgery and radiotherapy and chemotherapy 0 0
Treatment—12 months 11
  -Surgery alone 5 39
  -Radiotherapy alone 2 15
  -Chemotherapy alone 2 15
  -Surgery and radiotherapy 0 0
  -Radiation and chemotherapy 2 15
  -Surgery and radiotherapy and chemotherapy 2 15
Free flap 208 30 14
BIS T0 ≥ 10 218 31 14
BIS T1 ≥ 10 148 42 28
BIS T2 ≥ 10 141 28 20
BIS T3 ≥ 10 117 25 21
Time-Invariant Variables N Mean SD
Age 224 62.94 11.70
COPE DENIAL 219 3.07 1.65
N Frequency Percent
Female 224 72 32
French Language 224 115 51
Marital Status 224
  Married 142 63
  Divorced 47 21
  Single 23 10
  Widowed 12 5
Stage III/IV 222 161 73
Tumour site 223
Oropharynx 82 37
Oral 46 21
Larynx 37 17
Skin 15 7
Nasopharynx 11 5
Unknown Primary 12 5
Other 20 9
Cancer type—HPV+ 223 94 42
Physical function—ECOG 2+ 221 25 10