Table 3.
Outcome of humoral antibody determinations after CAR-T-cell therapy and COVID-19 mRNA vaccine in patients with “CAR-T before VAC”.
| CAR-T before VAC (32 Patients): Anti-Spike Protein IgG Antibodies (AU/mL) | |||
|---|---|---|---|
| after 2nd VAC (30 Patients) |
after 3rd VAC (23 Patients) |
after 4th VAC (3 Patients) |
|
| Results after 2 doses (no 3rd or 4th vaccination) | |||
| Pat. 1–8 | <12 | x | x |
| Pat. 9 | 143 | x | x |
| Results after 3 doses (no data on 2nd dose and no 4th vaccination) | |||
| Pat 10–11 | x | <12 | x |
| Results after 2 and 3 doses (no 4th vaccination) | |||
| Pat. 12–20 | <12 | <12 | x |
| Pat. 21 | <12 | 12.2 | x |
| Pat. 22 | <12 | 28.5 | x |
| Pat. 23 | <12 | 43.5 | x |
| Pat. 24 | <12 | 110 | x |
| Pat. 25 | <12 | 138 | x |
| Pat. 26 | 17.2 | 20.2 | x |
| Pat. 27 | 106 | 400 | x |
| Pat. 28 | 129 | <12 | x |
| Pat. 29 | 152 | >400 | x |
| Results after 2, 3, and 4 doses | |||
| Pat. 30 | <12 | <12 | 24.3 |
| Pat. 31 | 26.3 | <12 | 22.1 |
| Pat. 32 | 190 | >400 | 302 |
All results are in AU/mL; <12 AU/mL: negative anti-spike protein IgG antibody test result; >12 AU/mL: positive anti-spike protein IgG antibody test result; >100 AU/mL: clear positive result; VAC—vaccination; x—no data available.