Table 2.
Main clinical characteristics of patients harboring BRAF mutations in POPLAR/OAK cohort.
| Clinical Characteristics | Total (n = 35) |
Class 2 (n = 12) |
Class 3 (n = 10) |
Undefined Class (n = 13) |
p Value |
|---|---|---|---|---|---|
| Age, Mean (SD) | 64.1 (9.2) | 65.1 (7.5) | 65.4 (5.7) | 62.1 (12.5) | 0.415 |
| Sex, n (%) | |||||
| Female | 14 (40.0) | 6 (50.0) | 3 (30.0) | 5 (38.5) | 0.581 |
| Male | 21 (60.0) | 6 (50.0) | 7 (70.0) | 8 (61.5) | |
| Histology, n (%) | |||||
| Adenocarcinoma | 26 (74.3) | 10 (83.3) | 9 (90.0) | 7 (53.8) | 0.091 |
| Squamous | 9 (25.7) | 2 (16.7) | 1 (10.0) | 6 (46.2) | |
| Geographical origin, n (%) | |||||
| Caucasian | 27 (77.1) | 9 (75.0) | 7 (70.0) | 11 (84.6) | 0.669 |
| Asian | 6 (17.1) | 2 (16.7) | 2 (20.0) | 2 (15.4) | |
| Other | 2 (5.7) | 1 (8.3) | 1 (10.0) | 0 (0) | |
| Smoking habit, n (%) | |||||
| Yes | 33 (94.3) | 12 (100) | 9 (90.0) | 12 (92.3) | 0.431 |
| No | 2 (5.7) | 0 (0) | 1 (10.0) | 1 (7.7) |