An inverse relationship between vitamin D status and the risk of hospital-acquired infections. The maximum reduction of the infection rate was achieved when the serum 25(OH)D concentration exceeded 50 ng/mL (i.e., the background rate). This supports that 50 ng/mL as the minimum level required to overcome infections. Data presented as a multivariable logistic regression analysis with a locally weighted scatterplot. To demonstrate differences in hospitalisation risks, the percentage risk of infections at serum 25(OH)D concentrations of 10, 30, and 50 ng/mL are illustrated. The blue arrow shows a background risk of approximately 2.5% (modified after Quraishi, S.A, et al., 2014) [15].