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. 2022 Jul 21;14(14):2997. doi: 10.3390/nu14142997

Table 1.

When serum vitamin D levels are available, the doses provided in this table can be used for the longer-term maintenance of serum 25(OH)D concentration above 50 ng/mL (125 nmol/L). The table provides the initial bolus dose, weekly dose, frequency, and the duration of administration of oral vitamin D in non-emergency situations, in a non-obese, 70 kg adult. * (modified from Wimalawansa, S.J., 2012) [132,133]).

Serum Vitamin D (ng/mL) ** Vitamin D Dose: Using 50,000 IU Capsules: Initial and Weekly $ Duration (Number
of Weeks)
Total Amount
Needed to Correct Vit. D, Deficiency (IU, in Millions) #
Initial Bolus Dose (IU) Follow-Up: $$ The Number of 50,000 IU Caps/Week
<10 300,000 ×3 8 to 10 1.5 to 1.8
11–15 200,000 ×2 8 to 10 1.0 to 1.2
16–20 200,000 ×2 6 to 8 0.8 to 1.0
21–30 100,000 × 2 4 to 6 0.5 to 0.7
31–40 100,000 ×2 2 to 4 0.3 to 0.5
41–50 100,000 ×1 2 to 4 0.2 to 0.3

* A suitable daily or weekly maintenance dose to be started after completing the loading-dose schedule. The dose should be adjusted for those who are overweight (higher) or underweight (lower). ** To convert ng/mL to nmol/L, multiply the amount in ng by 2.5; One µg = 40 IU. $ Mentioned replacement doses can be taken as single, cumulative doses, two to three times a week spread out over a few weeks. $$ From the day one of week two onwards. # Estimated total vitamin D dose needed to replenish the body stores (i.e., the deficit) is provided in the last column.