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Effects of SGLT2 inhibitors on OCR. Effect of DMSO; DMSO + SGLT2 inhibitor (100 µM); cana, dapa, ertu, and empa on OCR and rotenone (2 µM) in (A) OCR as % average change from baseline and (B) OCR after 40 min (n = 16 (cana and dapa), n = 8 (ertu and empa), and n = 32 (DMSO); **** p < 0.0001, * p = 0.041, ns = not significant, n = replicates of samples). (C) ΔOCR for cana (n = 12).
