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. 2022 Jul 14;23(14):7761. doi: 10.3390/ijms23147761
AMD Age-related macular degeneration
CNV choroidal neovascularization
miRNA microRNA
NV AMD neovascular age-related macular degeneration
VEGFA Vascular endothelial factor A
CFH Complement Factor H
ARMS age-related maculopathy susceptibility
VEGF vascular endothelial growth factor
MAPK mitogen-activated protein kinase
VEGFR2 vascular endothelial growth factor receptor 2
PI3K phosphatidylinositol-3-kinase
PKB Protein kinase B
PERK protein kinase RNA-like endoplasmic reticulum kinase
HIF1A hypoxia-inducible factor-α
TGFβ Transforming Growth Factor β
ARPE-19 Adult Retinal Pigment Epithelial cell line-19
TGFβR2 Transforming Growth Factor β Receptor 2
KDR kinase insert domain receptor
VEGFR-2 vascular endothelial growth factor receptor-2
SPRED-1 Sprouty-related EVH1 domain-containing protein 1
RPE Retinal pigment epithelium
HUVECS Human Umbilical Vein Endothelial Cells
Limk2 LIM domain kinase 2
Pak4 p21-Activated kinase 4
Diaph1 homologs of Drosophila diaphanous
mTOR mammalian target of rapamycin
Scd2 stearoyl-CoA desaturase-2
TREM2 Triggering receptor expressed in myeloid/microglial cells-2
CNS Central nervous system
NF-κB nuclear factor kappa-light-chain enhancer of activated B cells
CHI3L1 Chitinase-3-like protein 1
ERK extracellular signal-regulated kinase
mTORC1 mammalian target of rapamycin complex 1
EZR ezrin
LAMP-1 lysosomal-associated membrane protein 1
NaIO3 Sodium iodate
Keap1 Kelch-like ECH-associated protein 1
Nrf2 Nuclear factor erythroid 2-related factor 2
FasL Fas Ligand
LPS lipopolysaccharide
RGS4 regulator of G protein signaling 4
IL-6 interleukin 6
MCP-1 monocyte chemoattractant protein-1
UVB Ultraviolet B
iASPP inhibitor of apoptosis stimulating protein of p53
apoB apolipoprotein B
FOXO1 forkhead box protein O1
ASO antisense oligonucleotides
TNFα Tumor necrosis factor α
HIF hypoxia-inducible factor
OCT Optical Coherence Tomography