Table 3.

Association between BNT162b2 and herpes infection events from large-scale controlled surveillance studies.

	Barda et al. [25]	Wan et al. [43]	Shasha et al. [40]	Birabaharan et al. [26]
Herpes zoster	RR: 1.43 EC: 15.8 per 100,000 people	iRR: 5.23 ‡ EC: 7 per 1 million doses	Non-sig.	Non-sig.
Herpes simplex virus infection	Non-sig.	-	-	-

Abbreviations/acronyms: EC: excess cases; HR: hazard ratio; iRR, incidence rate ratio; N/A: not available; RR: risk or relative ratio. Notes: (i) non-sig. means not statistically significant; (ii) if EC is not provided, it is not available; (iii) hyphen (-) denotes not available, that is, unexamined. ‡ The risk is limited to within two weeks of the first dose. The risk is similar at the iRR of 5.82 at 3–4 weeks after the first dose and 5.14 at 1–2 weeks after the second dose, but turns insignificant at 3–4 weeks after the second dose.