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DDR2 and POSTN promote in vivo tumor implantation. (A) Xenograft model showing increased tumor burden in mice co-injected with DDR2-depleted, POSTN-overexpressing CAFs and ES2 tumor cells. (B) Correlation between POSTN mRNA expression and DDR2 (and known ligands/targets) mRNA expression using TCGA data, and (C) Tumor microarray IHC data showing correlation between POSTN protein expression and DDR2 protein expression. ** p < 0.01.
