| CCS | Collisional cross section |
| CE | Capillary electrophoresis |
| ChEBI | Chemical entities of biological interest |
| CSV | Comma-separated values, spreadsheet/table data format |
| CV | Controlled vocabulary |
| DDA | Data-dependent acquisition |
| DI | Direct infusion |
| DI-MS | Direct infusion/shotgun mass spectrometry |
| DIA | Data-independent acquisition |
| DTIMS | Drift tube ion mobility spectrometry |
| FAIMS | High-field asymmetric-waveform ion mobility spectrometry |
| FAIR | Findable, accessible, indexable and retrievable |
| FDR | False discovery rate |
| GC | Gas chromatography |
| GL | Glycerolipids |
| GO | Gene ontology |
| GP | Glycerophospholipids |
| HILIC | Hydrophilic interaction liquid chromatography |
| HMDB | Human metabolome database |
| HTML | Hypertext markup language |
| HUPO | Human proteome organization |
| IMS | Ion mobility spectrometry |
| LC | Liquid chromatography |
| LSI | Lipidomics standards initiative |
| MALDI | Matrix-assisted laser desorption/ionization |
| MRM | Multiple reaction monitoring |
| MS | Mass spectrometry or mass spectrum |
| MS/MS | Tandem mass spectrometry or mass spectrum |
| MS1 | First order mass spectrum, single fragmentation |
| MS2 | Second order mass spectrum, fragmentation of ions from MS1, MS/MS |
| MSE | DIA with alternating low- and high-energy collision-induced dissociation |
| MSI | Metabolomics standards initiative |
| MSn | Higher (nth) order mass spectrometry or mass spectrum |
| NMR | Nuclear magnetic resonance |
| PRIDE | Proteomics identification database |
| PRM | Parallel reaction monitoring |
| PSI | HUPO Proteomics standards initiative |
| QA | Quality Assurance |
| QC | Quality Control |
| RPLC | Reversed-phase liquid chromatography |
| RT | Retention time |
| SFC | Supercritical fluid chromatography |
| SMILES | Simplified molecular input line entry system |
| SPLASH | Spectral hash |
| SRM | Selective reaction monitoring |
| TOF | Time-of-flight |
| TWIMS | Traveling wave ion mobility spectrometry |
| TXT | Semi-structured, text-based file format |
| VBA | Visual Basic for Applications |
| XLSX | MS Excel spreadsheet format |
| XML | Extensible markup language |